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Dan Elson introduction

 

Biography

Daniel Elson is a Professor in the Hamlyn Centre for Robotic Surgery, Institute of Global Health Innovation, Institute of Biomedical Engineering and Department of Surgery and Cancer, Imperial College London.  He completed a MSci and PhD in Physics at Imperial in 1999 and 2003 and became a Lecturer in the Institute of Biomedical Engineering in 2005.  Research interests are based around the development and application of photonics technology to surgical imaging and surgical robotics.  This includes developing imaging catheters for fluorescence lifetime imaging (FLIM), multispectral polarization sensitive laparoscopes with MEMS controlled spectral selection, illumination optics for flexible robotic endoscopes and optical detection of gold nanoparticles and thermal therapy. These projects are funded by sources including EPSRC, ERC, FP7, NIHR and Wellcome Trust. He has published over sixty five peer reviewed journal articles, ten book chapters and has contributed to over two hundred conferences.
 

Imperial College Staff Page

 

Recent papers
Scientific Reports (2016)
doi:10.1038/srep25953
 
International Journal of Computer Assisted Radiology and Surgery (2016)
doi:10.1007/s11548-016-1376-5 
 
 
 
Materials Science and Engineering C  Vol. 59 pp. 324-332 (2016) doi:10.1016/j.msec.2015.09.101 
 
 
 
 
Nanomedicine: Nanotechnology, Biology and Medicine, Vol 11(8) pp. 2083-2098 doi:10.1016/j.nano.2015.05.010  
 
Biomedical Optics Express Vol. 6(10) pp. 4179-4190 (2015) doi: 10.1364/BOE.6.004179 
 
 
 
 
  • Biomedical Optics Express Vol. 7(3) pp. 798-809 (2016)
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  • doi: 10.1364/BOE.7.000798
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    Int J CARS Vol. 10(12) pp. 1941-50. DOI 10.1007/s11548-015-1264-4 

    Available now: Fluorescence lifetime spectroscopy and imaging
    Fluorescence provides a powerful means of achieving molecular contrast in a wide range of biological and medical applications. For example, it can be used to detect the autofluorescence from naturally occurring fluorophores in biological tissues and can provide contrast between different states of diseased tissue.  Targeted probes can also be applied that localize in specific cellular locations and provide extrinsic image contrast or that bind to specific receptors on the cell membrane.  Over the past two decades not only have we seen remarkable advances in tissue diagnostic techniques based on fluorescence contrast, but we have also discovered the significant role that time-resolved or fluorescence lifetime techniques have to play in medical diagnosis. Until a decade ago progress in this area had been led by a small group of investigators; now many of the techniques are maturing and are ready to be adopted by innovative mainstream researchers and used in clinical settings. This broadly accessible book lays out the fundamentals, the state-of-the-art techniques and their current applications to help accelerate the use and proliferation of fluorescence techniques in tissue diagnostics for both research and clinical applications purposes.